ERC Starting Grant · 2025
Fungal pathogenicity emerging through functional adaptations to host environments
Fungal infections pose a serious medical threat, especially when they invade the bloodstream. The most common cause of fungal bloodstream infections is invasive candidemia, primarily attributed to a small group of pathogens, including Candida albicans, Nakaseomyces glabratus, Candida tropicalis, and Candida parapsilosis. Such infections are associated with crude mortality rates nearing 40%. Increasing numbers of very closely related yet non-pathogenic species have been sequenced and identified. However, a functional understanding of what differentiates them from their pathogenic counterparts is lacking. As fungal pathogenicity is a multifactorial trait that is influenced by intrinsic and…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.