ERC Starting Grant · 2022
Most microorganisms lack homeothermic regulation which subjects them to unpredictable fluctuations in environmental temperature. Nevertheless, many bacteria and archaea can grow across a large range of up to 40°C. Most biochemical reactions in bacteria occur in the highly crowded cytoplasm constituting a complex and dynamic interaction network of a cell. Temperature affects the rate of both intra- and intermolecular reactions, and large-scale perturbations by temperature could be disastrous to cellular function, homeostasis, and sub-cellular organization. It is still largely unknown, how temperature affects the physicochemical properties of the cytoplasm and what the consequences to…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.