Krasteva Lab

National Centre for Scientific Research (CNRS)

Ile-de-France (FR1) · France

ERC-funded
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Research focus

ERC Consolidator Grant · 2023

Structure and Regulation of Bacterial Biofilm-Promoting Exopolysaccharide Secretion Systems

Bacteria are commonly defined as unicellular organisms; however, they constantly exchange substances and information with their confrères and the environment, and can efficiently shelter themselves and achieve homeostasis by building multicellular collaborative macrocolonies called biofilms. Members of these sessile communities can undergo significant functional differentiation and are typically embedded in complex extracellular matrix that secures both mechanical protection and a medium for intercellular exchange. Importantly, the switch between sessile and motile life-styles in pathogenic bacteria can correlate directly with the development of chronic vs. acute infections, whereas…

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