ERC Starting Grant · 2023
Design of Nucleic Acid-Templated Ordered Protein Assemblies
Here I propose to create a new class of designed nanomaterials that will combine the advantageous features of protein design and DNA nanotechnology: nucleic acid-templated protein assemblies. I propose three different approaches that all utilize the addressability of nucleic acids on the nanometer to micrometer length scale to control size, shape, and composition of designed protein assemblies. In the first approach, the structural and mechanical properties of the assembly will be defined by the protein components, while the nucleic acid component serves merely to define the dimensions of the assembly and to introduce addressability to an otherwise symmetric, repetitive assembly. All…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.