Berg Lab

University of Newcastle

- · United Kingdom

ERC-funded
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ERC Advanced Grant · 2024

In with the good, out with the bad: understanding small molecule influx and efflux in gut Bacteroides.

The human gut microbiome can be considered a virtual organ that has a profound influence on many aspects of human health. While very diverse at the species level, the human gut microbiome is dominated by just two bacterial phyla, the Gram-positive Firmicutes and the Gram-negative Bacteroidetes. The Bacteroides genus belongs to the Bacteroidetes phylum and is the most abundant genus within the gut of western world populations. Due to their abundance and their well-characterised ability to break down dietary glycans that are inaccessible to the host, Bacteroides are keystone species that shape the human gut microbiome. However, to thrive within the gut, Bacteroides need to take up many small…

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